The visitors are the only remaining lower league side left in the tournament and are faced with a Herculean task of dumping out one of the frontrunners to go all the way.
After leading the Eredivisie until the end of January, PSV are now five places off the table after Saturday’s 2-1 loss to AZ Alkmaar.
Roger Schmidt’s men took the lead through Armando Obispo in the 19th minute before goals from Bruno Martins Indi and Jesper Karlsson changed the picture.
The defeat jeopardized the Roodwitten’s hopes, with Ajax now firmly in the driver’s seat in the race for the league’s name in May.
However, PSV are still forged in the Dutch Cup thanks to their 2-0 and 2-1 victories over Fortuna Sittard and Telstar respectively.
Next up is a 16-game circular clash against an opponent who have lost seven of their last 8 meetings, dating back to 2014.
Tuesday’s hosts lost the most recent encounter of 2020 that took place at the same festival and this time they will be eager for revenge.
NAC Breda have to knock out a third team in a row from the Eredivisie after knocking out Utrecht and, more recently, PEC Zwolle in the final two rounds.
Edwin de Graaf’s men have failed to reflect that form in the Eerste Divisie, where they have not won any of their last six games and are in eleventh place of late.
The Pearl of the South far surpassed last season’s performance in this tournament, eliminating in the round of 16 via Groningen.
Just under a decade after their name in 1973, Tuesday’s visitors can take a big step forward to repeat the feat with a full-time victory.
New signing Joey Veerguy was named the fit man in the latest circular against Telstar and will look to deliver the goods once again.
Eran Zahavi has made three consecutive appearances off the bench since his return from injury but could be named in the starting XI for this one.
Noni Madueke, Ryan Thomas, Mees Kreekels, Carlos Vinicius, Shurandy Sambo and Andre Ramalho will be absent for the hosts.
Odiseo Velanas contributed directly to any of his team’s goals this weekend, and the 23-year-old is someone to keep an eye on.
Breda will be without Dutch striker Mario Bilate, who has not played since September due to a long-term knee problem.
Possible PSV Eindhoven lineup: Drommel; Mwene, Bosacgli, Bishop, Max; Gutierrez, Veerman, Gotze; Zahavi, Doan, Mist
Possible NAC Breda XI: Olij; Mashart, Adilehou, Malone, Hilterman; Seuntjens, Cagro, Agougil; Velanas, banished, by Rooy
Experience often comes in handy in matches of this nature and, in fact, PSV have a lot compared to their opponents. We hope that they will emerge triumphant and become one of the four finalists.
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a PSV Eindhoven win with a probability of 74.99%. A draw had a probability of 14.7% and a win for NAC Breda had a probability of 10.29%.
The maximum probable score for PSV Eindhoven to win was 2-0 with a probability of 9. 64%. The next maximum probable scores for this final result were 2-1 (8. 95%) and 3-0 (8. 73%). The maximum probable result was 1-1 (6. 59%), while for a NAC Breda victory it was 1-2 (3. 06%). The actual result of 4-0 was predicted with a probability of 5. 9%. Our team and Sports Mole knowledge research also did not predict that PSV Eindhoven would win this match.