Meanwhile, Zenit St. Petersburg is immersed in a fierce race for the name in league-leading Lokomotiv Moscow Russia, despite their huge goal difference.
Leipzig are in fifth place in the Bundesliga, but after 8 games, one point separates them from league leaders Borussia Mönchengladbach.
In fact, there are only two differences between Gladbach and Bayer Leverkusen, ninth, while Germany enjoys a first wave of teams competing for the title.
Leipzig’s participation in this league war would possibly be a distraction in their Champions League campaign, having lost 2-0 at home to a Lyon side struggling to remain compatible in Ligue 1.
The German team remained unbeaten in all competitions until the end of September. Since then, they have not won any of their last 4 matches in competition, losing twice.
Things are also tight at the top of the Russian Premier League table, with just three points among the top five teams.
However, Zenit fared better in Europe than Leipzig despite their domestic distractions, adding four points to three for the German team and occupying the top of the organization thanks to goals scored.
The Russian team has performed at this level of the festival in recent seasons, winning seven of their last 10 such matches, losing two and drawing them.
Much of his good fortune in recent times is due to the form of towering striker Artem Dzyuba, who scored or assisted in his eight Champions League organisational appearances with Zenit, scoring seven goals and providing three assists.
Leipzig Form: WWLDDFormulaire Zenit: WWLWWW
Leipzig head coach Julian Nagelsmann is one of three key players due to injury as his team hosts Zenit on Wednesday.
Centre-back Ibrahima Konate is absent due to a muscle problem suffered in the loss to Lyon, attacking midfielder Hannes Wolf is absent with a leg injury and his compatriot recruited this summer, Patrik Schick, has been suffering from an ankle since being loaned out to Roma.
However, Leipzig are the only team frustrated by the lack of a new signing.
Zenit coach Sergei Semak will not be able to play Brazilian winger Malcom from Barcelona due to a hip injury that could sideline him until Christmas.
The striker joins interesting centre-back Emanuel Mammana, who has been absent for a long time due to a serious knee, on the bench.
Leipzig’s possible 11: Gulacsi; Klostermann, Upamecano, Orban, Halstenberg; Sabitzer, Laimer, Demme, Forsberg; Poulsen, Werner
Zenit’s imaginable starting lineup: Kerzhakov; Karavayev, Ivanovic, Rakitskiy, Santos; Chatov, Ozdoyev, Barrios, Driussi; Dzyuba, Azmoun
Leipzig had the defense in Germany last season and is a strong team in defense. Despite their recent difficulties of form, they have enough quality in the total team to make the merit of their home count this time and achieve an important, if close, victory.