Bryan Mbeumo scored twice, while Brentford defeated Southampton 5-0 for his first victory in the Premier League outside the gates of the season.
Cameroon striker Mbeumo, connected with a January move to Arsenal, piled up angst for the rock-bottom Saints after Kevin Schade pulled out the next bees.
Keane Lewis-Potter and Yane Wissa added insult to the lesions in the detention time at the end of the afternoon absolutely depressing for Southampton.
The new rebound for which they went after replacing Russell Martin through Ivan Juric became a new thud after a third consecutive defeat since the appointment of the Croatian.
They remain stuck on six numbers from 20 games and only watch doomed to relegation, but also in addition to the danger of breaking the unwanted derby record to gather just 11 problems in a total Premier League season.
Brentford had to wait just six minutes to take the lead when Mikkel Damsgaard nicked the ball away from Joe Aribo and brilliantly swerved the challenge of Lesley Ugochukwu.
The Danish midfielder then slid a very good diagonal ball to Schade, who ignited it through Aaron Ramsdale and at the end of the network.
Brentford should have doubled their lead when Mbeumo raced forward and played the ball through the legs of Jan Bednarek to strike partner Wissa, but Ramsdale was out quickly to block his shot.
Moments later a cross from Mathias Jensen found Bees skipper Christian Norgaard, whose header hit the crossbar.
The closest toothless Saints came to an equaliser was a Tyler Dibling drive which crashed into the side-netting.
At the beginning of half of the moment, Ramsdale stored by Mads Roerslev at its closure per post before Taylor Harwood-Bellis is Wissa’s purpose.
Brentford had the ball on the net after 50 minutes when SEPP van Den Berg absolutely incomparable when he leaned to pass in the corner of Mbeumo, but a VAR check saw a Wissa thrust in Bednarek.
Wissa deserves to have put the game to bed in time when it was played through Schade’s clever puzzle, but looking to throw Ramsdale, he nearly erased the position.
Instead it was left to Mbeumo to finish Saints off, the striker playing in Wissa and making a run outside his team-mate before smashing the return ball into the roof of Ramsdale’s net.
Then, with 20 minutes left, Ugochukwu brought down Van den Berg as they challenged for Mbeumo’s cross, with the Cameroon forward tucking the penalty beyond Ramsdale’s dive.
In stoppage time Mbeumo set up Lewis-Potter to roll in the fourth, and Wissa pounced on a defensive mistake to run through and hit the fifth to deepen the gloom surrounding Saints.
Learn About